Cancer BiologyCancersPeer-reviewed
Dynamic PD-L1 Regulation Shapes Tumor Immune Escape andResponse to Immunotherapy
Bruce Pell, Aigerim Kalizhanova, Aisha Tursynkozha…·Yang Kuang
The paper models PD-L1 dynamics in response to immunotherapy, showing that PD-L1 upregulation leads to treatment failure, while PD-1/PD-L1 blockade improves anti-tumor responses.