Short-term assessment of subfoveal injection of AAV2-hCHM gene augmentation in choroideremia using adaptive optics ophthalmoscopy
Jessica I. W. Morgan, Yu You Jiang, Grace K. Vergilio, Leona W. Serrano, Denise J. Pearson, Jean Bennett, Albert M. Maguire, Tomás S. Alemán
The paper assesses the short-term effects of AAV2-hCHM gene injections on cone mosaic integrity in CHM patients using AOSLO and finds preservation of the mosaic with minor foveal thinning.
bioRxiv · Sep 17, 2021 · PreprintNeuroscience