Life-cycle trajectory inference links temperature-gated progenitors to reproductive fate
Gaurav Vaidya, Elena Lagodny, Aishwarya Girish, Ana Mellado Fuentes, Eric J. Ross, Sofia M. C. Robb, Kristina Mirkes, Deniz Yavru, Arif ul Maula Khan, Christian Tischer, Michael W. Dorrity, Hanh Thi-Kim Vu
The paper uses single-cell transcriptomics to infer life-cycle trajectories in planarians, showing how temperature gates stem cell fate to determine reproductive strategies.
bioRxiv · Jun 29, 2026 · PreprintDevelopmental Biology