The LINC complex regulates Achilles tendon elastic modulus, Achilles and tail tendon collagen crimp, and Achilles and tail tendon lateral expansion during early postnatal development.
Nicholas M. Pancheri, Jordan T. Daw, Destinee Ditton, Nathan R. Schiele, Scott Birks, Gunes Uzer, Calvin L. Jones, Brian T. Penney, Sophia K. Theodossiou
This study shows that disrupting the LINC complex in mice affects tendon mechanical properties and collagen crimp structure differently in energy-storing and limb-positioning tendons.
bioRxiv · Nov 13, 2023 · PreprintDevelopmental Biology