Dhruv D. Jatkar

Optimization of heuristic logic synthesis by iteratively reducing circuit substructures using a database of optimal implementations

This paper improves heuristic logic synthesis by using a database of optimal 4-input Boolean implementations to reduce gate count in larger circuits, achieving average improvements of 5.16% and 4.54% for 5- and 6-input circuits respectively.

Paradoxical gene regulation explained by competition for genomic sites

The paper demonstrates that increasing activator expression can reduce target gene expression by displacing repressor from decoy sites, explaining paradoxical gene regulation through competition for genomic binding sites.

Modeling and minimization of dCas9-induced competition in CRISPRi-based genetic circuits

This paper models and minimizes dCas9 competition in CRISPRi-based genetic circuits to improve their performance and dynamic range.