Mass spectrometric profiling of estrogen and estrogen metabolites in human stool and plasma partially elucidates the role of the gut microbiome in estrogen recycling
Vince W Li, Tien Sy Dong, Diana Funes, Laura Hernandez, Srinivasa T. Reddy, Emeran A. Mayer, Lin Chang, David Meriwether
The paper develops an LC-MS/MS method to measure estrogens and metabolites in human stool and plasma, finding correlations between stool estrogen levels, menstrual cycle phase, and gut microbial enzyme gene copy numbers.
bioRxiv · Aug 7, 2024 · PreprintMolecular Biology