Public and private human T cell clones respond differentially to HCMV antigen when boosted by CD3 co-potentiation
Laura R.E. Becher, Wendy K. Nevala, Shari S. Sutor, Megan Abergel, Michele M. Hoffmann, Christopher A. Parks, Larry R. Pease, Adam G. Schrum, Svetomir N. Markovic, Diana Gil
This study shows CD3 co-potentiation enhances expansion of public and private T cell clones responding to HCMV antigens, with distinct expansion patterns based on antigen strength and TCR status.
bioRxiv · Jul 8, 2020 · PreprintImmunology