Epigenetically Modified DNAzyme Walkers for Simultaneously Imaging of MGMT and FTO Activity in Living Cancer Cells
Yewei Li, Fuling Liang, Mingda Li, Yanfang Gong, Die Long, Huanhuan Sun, Min Hou, Mingyan Jiang
This paper develops DNAzyme-powered walkers to image MGMT and FTO demethylase activities in live cancer cells, enabling simultaneous detection of these enzymes' functions.
bioRxiv · Jun 15, 2025 · PreprintMolecular Biology