Differential Sensitivity of HSV-1 and PRV to IFN-{lambda} Reveals a Neuron-Specific Antiviral Role for RSAD2
Stephanie N. Salazar, Khanh T. Y. Luong, Audrey Danielle Loaiza, Dillon Cheng, Nir Drayman, Orkide Ö. Koyuncu
This study compares HSV-1 and PRV sensitivity to IFN-λ, showing HSV-1's neuron-specific resistance and identifying RSAD2 as a key antiviral factor in neurons.
bioRxiv · Jun 2, 2026 · PreprintMicrobiology