CHD8 regulates gut epithelial cell function and affects autism-related behaviours through the gut-brain axis
Ipsita Chatterjee, Dimitry Getselter, Nasreen Ghaneem, Shai Bel, Evan Elliott
This study shows that CHD8 haploinsufficiency in mice causes gut dysfunction and anxiety-like behaviors, linking gut health to autism-related behaviors through the gut-brain axis.
bioRxiv · Oct 2, 2021 · PreprintNeuroscience