Upregulating ANKHD1 in PS19 mice reduces Tau phosphorylation and mitigates Tau-toxicity-induced cognitive deficits
Xiaolin Tian, Nathan N. Le, Yuhai Zhao, Dina Alawamleh, Andrew M. Schwartz, Lauren F Meyer, Elizabeth Helm, Chunlai Wu
This study shows that increasing ANKHD1 in PS19 mice reduces Tau phosphorylation and cognitive deficits by enhancing autophagy.
International Journal of Molecular Sciences · Aug 4, 2025Peer-reviewedNeuroscience