Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs
Artem Baranovsky, Timofei M. Ivanov, Marina Granovskaya, Dmitri Papatsenko, Dmitri Davidovich Pervouchine
The paper analyzes RNA-seq data from TCGA to assess stemness and proliferation gene expression across tumor types, finding high heterogeneity and questioning the use of stemness markers in cancer diagnostics.
bioRxiv · Sep 2, 2021 · PreprintBioinformatics