Effects of chronic exposure to fluoxetine, eicosapentaenoic acid, and lipopolysaccharide on behavior and hippocampal transcriptome in the rat model of prolonged chronic unpredictable stress
Konstantin A. Demin, Tatiana O. Kolesnikova, David S. Galstyan, Nataliya A. Krotova, Nikita P. Ilyin, Ksenia A. Derzhavina, Maria V. Seredinskaya, Yuriy M. Kositsyn, Dmitry V. Sorokin, Maria O. Nerush, Abubakar-Askhab S. Khaybaev, Sofia A. Pushkareva, Elena V. Petersen, Murilo S. de Abreu, Alexey Masharsky, Allan V. Kalueff
This study examines the effects of chronic exposure to fluoxetine, EPA, and LPS on behavior and hippocampal transcriptome in a rat model of prolonged chronic unpredictable stress, identifying potential therapeutic targets.
bioRxiv · Dec 5, 2021 · PreprintNeuroscience