This paper describes a method using fluorescent protein release to assess cytotoxicity, showing differences in sensitivity to capecitabine across 3D cultures.

BMC Molecular and Cell Biology · Jan 28, 2025Peer-reviewedPharmacology & Toxicology

Behavioral and neurochemical effects of novel N-Benzyl-2-phenylethylamine derivatives in adult zebrafish

Konstantin A. Demin, Olga V. Kupriyanova, Vadim A. Shevyrin, Ksenia A. Derzhavina, Nataliya A. Krotova, Nikita P. Ilyin, Tatiana O. Kolesnikova, David S. Galstyan, Yurii M. Kositsyn, Abubakar-Askhab S. Khaybaev, Maria V. Seredinskaya, Yaroslav A. Dubrovskii, Raziya G. Sadykova, Maria O. Nerush, Mikael S. Mor, , Allan V. Kalueff

This study evaluates the behavioral and neurochemical effects of ten novel N-Benzyl-2-phenylethylamine derivatives in adult zebrafish, identifying compounds with hallucinogenic-like and anxiolytic properties.

ACS Chemical Neuroscience · Jun 7, 2022Peer-reviewedNeuroscience

Effects of chronic exposure to fluoxetine, eicosapentaenoic acid, and lipopolysaccharide on behavior and hippocampal transcriptome in the rat model of prolonged chronic unpredictable stress

Konstantin A. Demin, Tatiana O. Kolesnikova, David S. Galstyan, Nataliya A. Krotova, Nikita P. Ilyin, Ksenia A. Derzhavina, Maria V. Seredinskaya, Yuriy M. Kositsyn, Dmitry V. Sorokin, Maria O. Nerush, Abubakar-Askhab S. Khaybaev, Sofia A. Pushkareva, Elena V. Petersen, Murilo S. de Abreu, Alexey Masharsky, Allan V. Kalueff

This study examines the effects of chronic exposure to fluoxetine, EPA, and LPS on behavior and hippocampal transcriptome in a rat model of prolonged chronic unpredictable stress, identifying potential therapeutic targets.

bioRxiv · Dec 5, 2021 · PreprintNeuroscience