Author

Dominic Sinibaldi

AstraZeneca (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:statistical model· 1

Frequent Co-Authors

Carlos P. RocaiD· 1 shared Elena EyreiD· 1 shared Jonathan MangioniD· 1 shared Oleg SysoeviD· 1 shared Philip M. R. TedderiD· 1 shared Silvia GalaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Carlos P. RocaORCID

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1 paper

Recent·Most cited

Regulation Flow Analysis discovers molecular mechanisms of action from large knowledge databases

Carlos P. Roca, Oleg Sysoev, Elena Eyre, Silvia Galan, Dominic Sinibaldi, Philip M. R. Tedder, Jonathan Mangion

This paper introduces Regulation Flow Analysis (RFA), a method that generates causal hypotheses of drug mechanisms using knowledge graphs, improving understanding of biological processes and drug development.

bioRxiv · Jun 15, 2025 · PreprintBioinformatics