Author

Silvia Galan

AstraZeneca (Spain)ORCID 0000-0002-4795-8326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Carlos P. RocaiD· 1 shared Dominic Sinibaldi· 1 shared Elena EyreiD· 1 shared François SerraiD· 1 shared Jonathan MangioniD· 1 shared Marc A. Martı́-RenomiD· 1 shared Oleg SysoeviD· 1 shared Philip M. R. TedderiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBioinformatics

Carlos P. RocaORCID

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2 papers

Recent·Most cited

Regulation Flow Analysis discovers molecular mechanisms of action from large knowledge databases

Carlos P. Roca, Oleg Sysoev, Elena Eyre, Silvia Galan, Dominic Sinibaldi, Philip M. R. Tedder, Jonathan Mangion

This paper introduces Regulation Flow Analysis (RFA), a method that generates causal hypotheses of drug mechanisms using knowledge graphs, improving understanding of biological processes and drug development.

bioRxiv · Jun 15, 2025 · PreprintBioinformatics

Identification of chromatin loops from Hi-C interaction matrices by CTCF-CTCF topology classification

Silvia Galan, François Serra, Marc A. Martı́-Renom

The paper introduces LOOPbit, a method to detect chromatin loops from Hi-C data by classifying CTCF-CTCF interactions, achieving higher enhancer-promoter loop detection than existing tools.

NAR Genomics and Bioinformatics · Jan 13, 2022Peer-reviewedBioinformatics