Efficient and scalable de novo protein design using a relaxed sequence space
Christopher Frank, Ali Khoshouei, Yosta de Stigter, Dominik Schiewitz, Shihao Feng, Sergey Ovchinnikov, Hendrik Dietz
This paper introduces a method for efficient de novo protein design using a relaxed sequence space approach, demonstrating successful experimental production of over 50 proteins with desired structural properties.
bioRxiv · Feb 24, 2023 · PreprintSynthetic Biology