Mechanical environment afforded by engineered polymer hydrogel critically regulates survival of neural stem cells transplanted in the injured spinal cord via Piezo1-mediated mechanotransduction
Hee Hwan Park, Y. G. Kim, Byeong Seong Jang, Simay Genişcan, Dong Hoon Hwang, Yeojin Seo, Seung‐Ah Jee, Hyo Gyeong Seo, Hyung Soon Kim, Ariandokht Einisadr, Ho‐Jeong Kim, S.H. Lee, Sangwoo Kwon, Kyung Sook Kim, Kang In Lee, , Byung Gon Kim
This study shows that the mechanical stiffness of a hydrogel scaffold affects neural stem cell survival in spinal cord injuries through Piezo1 mechanotransduction.
Advanced Science · Nov 3, 2025Peer-reviewedNeuroscience