Patient-Derived Liver Cancer Organoids Reflect Tumor Biology and Their Growth Phenotype Correlates with Clinical Outcomes
Yeon Su Kim, Yoon-Ha Go, Hyung Sun Kim, 서재휘, Dong oh Kim, Dong‐Youn Hwang, Jongman Yoo, Wookyeom Yang, Jin Hong Lim
Organoids grew from 13 of 27 resected hepatocellular carcinomas. The sequenced lines kept parental mutations, and solid rather than cystic growth marked shorter progression-free survival (HR 13.91).
bioRxiv · Oct 6, 2026 · PreprintCancer Biology✦ In-depth digest