Sequence-based drug design using transformers
Shengyu Zhang, Donghui Huo, Robert I. Horne, Yumeng Qi, Sebastian Pujalte Ojeda, Aixia Yan, Michele Vendruscolo
This paper introduces Ligand-Transformer, a deep learning framework for predicting protein-ligand interactions, and demonstrates its application in identifying inhibitors for specific targets and studying disordered proteins.
bioRxiv · Nov 27, 2023 · PreprintBioinformatics