The Lag3 KIEELE motif couples HPK1 to metabolic and functional regulation of Foxp3+ regulatory T cells
Giha Kim, Dongkyun Kim, Sohee Kim, Booki Min
This study identifies the Lag3 KIEELE motif as essential for Treg cell suppression by linking HPK1 signaling to metabolic and functional regulation.
bioRxiv · Oct 3, 2026 · PreprintImmunology