Pulmonary Matrix Derived Hydrogels from Patients with Idiopathic Pulmonary Fibrosis Induce a Proinflammatory State in Lung Fibroblasts In Vitro
Jorge G. Fernandez Davila, DW Moore, Joseph Kim, JA Khan, Amit Kumar Singh, Merte Lemma, CS King, S.D. Nathan, L. Raposo Rodríguez, G. Grant, Jeffrey Lawrence Moran
This study uses patient-derived hydrogels to show IPF fibroblasts exhibit increased inflammation and altered contractility in 3D culture compared to 2D.
bioRxiv · May 3, 2023 · PreprintMolecular Biology