Force Induces a Collective Inactivity in Dyneins to Auto-Regulate Bidirectional Transport of Vesicles
Dwiteeya Chaudhury, Aniket Kumar, Paulomi Sanghavi, Sudipto Muhuri, Mithun Kumar Mitra, Roop Mallik
The paper shows that dynein teams become collectively inactive under force, allowing kinesin to reverse cargo and regulate bidirectional transport.
bioRxiv · Oct 9, 2026 · PreprintCell Biology