Roop Mallik

The paper shows that dynein teams become collectively inactive under force, allowing kinesin to reverse cargo and regulate bidirectional transport.

This study identifies lysosomal acid lipase (LIPA) as a key enzyme regulating cholesterol metabolism during phagosomal maturation, linking lipid catabolism to antimicrobial defense.

The paper shows that targeting kinesin-1 on lipid droplets reduces serum lipids in cell culture and zebrafish, with no toxicity or lipid accumulation.