Evolutionary rate covariation identifies SLC30A9 (ZnT9) as a mitochondrial zinc transporter.
A. Kowalczyk, O. Gbadamosi, K. Kolor, J. Sosa, C. St Croix, G. Gibson, M. Chikina, E. Aizenman, N. Clark, K. Kiselyov
The paper uses evolutionary rate covariation to predict the mitochondrial localization of SLC30A9, which is confirmed experimentally as a zinc exporter.
bioRxiv · Apr 22, 2021Evolutionary Biology