Simplified Molecular Classification of Lung Adenocarcinomas Based on EGFR, KRAS, and TP53 Mutations
R. Ruiz-Cordero, J. Ma, A. Khanna, G. Lyons, W. Rinsurongkawong, R. Bassett, M. Guo, M. J. Routbort, J. Zhang, F. Sloulidis, J. V. Heymach, E. B. Roarty, Z. Tang, L. J. Medeiros, K. P. Patel, , S. Roy-Chowdhuri
This paper classifies lung adenocarcinomas into six subtypes based on EGFR, KRAS, and TP53 mutations, finding associations with prognosis and validating the classification against clinical outcomes.
bioRxiv · Jan 21, 2019Cancer Biology