Insight into the mechanism of H+-coupled nucleobase transport
J. Weng, X. Zhou, P. Wiriyasermkul, Z. Ren, X. Yan, K. Chen, E. G. Iturbe, M. Zhou, M. Quick
The paper reports the structure and function of PurTCp, a NAT family transporter from Colwellia psychrerythraea, showing it transports purines via H+-dependent mechanism and identifies a critical aspartate residue.
bioRxiv · Dec 20, 2021 · PreprintBiochemistry