Molecular Dynamics Simulations of HLA-CW4-B2M-KIR2DL1 Protein and Homology Modeling of a Complex Associated with Psoriasis Disease (HLA-CW6-B 2M-KIR2DS1)
M. H. Almatarneh, A. M. Alqaisi, E. K. Ibrahim, G. G. Kayed, J. W. Hollett
This study uses molecular dynamics simulations to analyze the HLA-Cw4-β2m-KIR2DL1 complex with a peptide, revealing β2m's lack of direct interaction and its minimal effect on complex dynamics, aiding in drug design for psoriasis.
bioRxiv · Dec 20, 2021 · PreprintBiochemistry