The CD8+ T cell landscape of human brain metastases
L. J. Sudmeier, K. B. Hoang, E. K. Nduom, A. Wieland, S. G. Neill, M. J. Schniederjan, S. S. Ramalingam, J. J. Olson, R. Ahmed, W. H. Hudson
This study characterizes CD8+ T cell phenotypes and spatial distribution in brain metastases using single-cell RNA-sequencing and spatial transcriptomics, revealing distinct subpopulations and their functional states.
bioRxiv · Aug 3, 2021Immunology