Identification of differential gene expression pattern in lens epithelial cells derived from cataractous and non-cataractous lenses of Shumiya cataract rat
H. Ishida, T. Shibata, Y. Nakamura, Y. Ishigaki, H. Sasaki, D. P. Singh, E. Kubo
This study identifies gene expression changes in lens epithelial cells of Shumiya cataract rats, finding downregulation of genes involved in fiber differentiation and suggesting cholesterol deficiency contributes to cataract formation.
bioRxiv · May 19, 2020Cell Biology