Substitution of nucleotide-sugar by trehalose-dependent glycogen synthesis pathways in Chlamydiales underlines an unusual requirement for storage polysaccharides within obligate intracellular bacteria
M. Colpaert, D. Kadouche, M. Ducatez, T. Pillonel, C. Kebbi Beghdadi, U. Cenci, B. Huang, M. Chabi, E. Maës, B. Coddeville, L. Couderc, H. Touzet, F. Bray, C. Tirtiaux, S. Ball, , C. Colleoni
This study identifies a unique glycogen synthesis pathway in Chlamydiales using trehalose instead of ADP-Glucose, highlighting its role in survival and infectivity.
bioRxiv · Jun 2, 2020 · PreprintMicrobiology