Nucleosome topology and DNA sequence modulate the engagement of pioneer factors SOX2 and OCT4
F. C. Malaga Gadea, E. N. Nikolova
This study investigates how nucleosome topology and DNA sequence influence the binding of pioneer factors SOX2 and OCT4, revealing position- and sequence-dependent interactions and conformational dynamics.
bioRxiv · Jan 18, 2022 · PreprintBiochemistry