Kidins220 regulates the development of B cells bearing the {lambda} light chain
A.-M. Schaffer, G. J. Fiala, M. Hils, E. Natali, L. Babrak, L. A. Herr, M. Rizzi, E. Miho, W. Schamel, S. Minguet
This study shows Kidins220 regulates λLC B cell development by supporting precursor survival and optimizing pre-BCR/BCR signaling for λLC locus opening and recombination.
bioRxiv · Apr 4, 2022Immunology