2-amino-1,3-benzothiazole-6-carboxamide Preferentially Binds the Tandem Mismatch Motif r(UY:GA)
E. Nikonowicz, S. Zhang, A. T. Chang, L. Song, L. Chen
The paper identifies a small molecule that specifically binds to a tandem UU:GA mismatch motif in RNA, highlighting the importance of motif context for small molecule targeting.
bioRxiv · Jun 11, 2020Biochemistry