Analysis of nucleic acids extracted from rapid diagnostic tests reveals a significant proportion of false positive test results associated with recent malaria treatment
S. Hosch, C. A. Yoboue, O. T. Donfack, E. A. Guirou, J.-P. Dangy, M. Mpina, E. Nyakurungu, K. Blöchliger, C. A. Guerra, W. P. Phiri, M. O. Ayekaba, G. Garcia, M. Tanner, C. Daubenberger, T. Schindler
The paper analyzes nucleic acids from malaria RDTs to show that 4.7% of results were false-negative and 28.4% false-positive, linked to low parasite density and PfHRP2 antigen persistence after treatment.
bioRxiv · May 12, 2021Microbiology