Author

E. Shvarov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1

Frequent Co-Authors

B. Fatykhov· 2 shared G. V. Ponomarev· 2 shared M. D. Kazanov· 2 shared M. S. Gelfand· 2 shared A. A. Chervova· 1 shared A. A. Denisova· 1 shared A. Chervova· 1 shared A. Koblov· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

B. Fatykhov

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2 papers

Recent·Most cited

APOBEC mutagenesis is low in most types of non-B DNA structures, unlike other types of cancer mutagenesis

G. V. Ponomarev, B. Fatykhov, V. A. Nazarov, R. Abasov, E. Shvarov, N.-V. Landik, A. A. Denisova, A. A. Chervova, M. S. Gelfand, M. D. Kazanov

The paper shows APOBEC mutagenesis is not enriched in most non-B DNA structures, unlike other cancer mutagenesis, and is lower in G-quadruplexes and Z-DNA regions.

bioRxiv · Oct 12, 2021 · PreprintCancer Biology

Analysis of gene expression and mutation data points on contribution of transcription to the mutagenesis by APOBEC enzymes

A. Chervova, B. Fatykhov, A. Koblov, E. Shvarov, J. Preobrazhenskaya, D. Vinogradov, G. V. Ponomarev, M. S. Gelfand, M. D. Kazanov

This study analyzes gene expression and whole genome sequencing data to assess the role of transcription in APOBEC-induced mutagenesis compared to replication, finding similar impacts from both processes in transcribed regions.

bioRxiv · Apr 14, 2021Cancer Biology