Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy
Y. Wang, D. R. Bergman, E. Trujillo, A. A. Fernald, L. Li, A. T. Pearson, R. F. Sweis, T. L. Jackson
This study compares ODE and ABM models to show how spatial components affect immunotherapy outcomes in tumors with different antigenicity and CTL killing mechanisms.
bioRxiv · Jul 3, 2024Cancer Biology