CRISPR/Cas9-mediated Generation of COL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa
F. Alipour, M. Ahmadraji, E. Yektadoust, P. Mohammadi, H. Baharvand, M. Basiri
The paper generates COL7A1-deficient keratinocyte cell lines using CRISPR/Cas9 to model RDEB and shows reduced type VII collagen expression and increased cell motility.
bioRxiv · Jun 15, 2023 · PreprintCell Biology