KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy
Katrin Linda, Elly Lewerissa, Anouk H. A. Verboven, Michele Gabriele, Monica Frega, Teun M. Klein Gunnewiek, Lynn Devilée, Edda Ulferts, Marina P. Hommersom, Astrid R. Oudakker, Chantal Schoenmaker, Hans van Bokhoven, Dirk Schubert, Giuseppe Testa, David A. Koolen, , Nael Nadif Kasri
This study shows that KANSL1 deficiency leads to oxidative stress-induced autophagy, causing synaptic dysfunction and neuronal network impairments in neurons.
Autophagy · Jul 21, 2021Peer-reviewedNeuroscience