Predicting bacterial fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning
Ethan Bustad, Edson Petry, Oliver Gu, Braden T Griebel, Tige R. Rustad, David R. Sherman, Jason H. Yang, Shuyi Ma
The paper predicts Mtb fitness using a transcription factor activity-based machine learning model trained on RNA-seq data and regulatory network analysis.
Frontiers in Tuberculosis · Apr 2, 2025Peer-reviewedSystems Biology