Cooperation between Noncanonical Ras Network Mutations in Cancer
Edward C Stites, Paul C Trampont, Lisa B Haney, Scott F Walk, Kodi S Ravichandran
The paper models synergistic combinations in the Ras network and finds that NF1 mutations can amplify effects of noncanonical Ras mutants, suggesting network instability may drive cancer.
bioRxiv · May 6, 2014Cancer Biology