MechanoAge, a machine learning platform to identify individuals susceptible to breast cancer based on mechanical properties of single cells
Stefan Hinz, Sturla Magnus Grøndal, Masaru Miyano, Jennifer C. Lopez, Kristen L. Cotner, Taylor Thomsen, Chang Chen, Edward J Hester, Lisa D. Yee, Victoria L. Seewaldt, James B. Lorens, Lydia Lee Sohn, Mark A. LaBarge
This paper develops MechanoAge, a machine learning tool that identifies breast cancer risk based on single-cell mechanical properties and introduces mechano-RISQ to quantify risk-related mechanical deviations.
EBioMedicine · Apr 24, 2026Peer-reviewedCancer Biology