Y-Family DNA Polymerases Have Three Structural Elements That Promote Accurate dCTP Insertion And Minimize dATP/dGTP/dTTP Misinsertion Opposite a N2-dG Adduct of Benzopyrene
Gabriel Sholder, Peter Tonzi, Sushil Chandani, Edward L. Loechler
The paper identifies three structural elements in Y-Family DNA polymerases that enhance dCTP insertion accuracy and reduce misinsertion opposite a BP-N2-dG adduct.
bioRxiv · Jan 31, 2019 · PreprintMolecular Biology