Rare coding variation in OCD implicates shared genes with other psychiatric disorders
Seulgi Jung, Matthew Delayne Halvorson, Nancy Pedersen, Marina Natividad Avila, Maria Niarchou, EGOS, NORDiC, Bernie Devlin, Kathryn Roeder, James J. Crowley, Joseph D. Buxbaum, Dorothy E. Grice
This study identifies rare coding variants contributing to OCD risk and shows genetic overlap with CTD and neurodevelopmental disorders, while showing minimal overlap with bipolar disorder and schizophrenia.
medRxiv · Dec 23, 2025 · PreprintGenetic & Genomic Medicine