Dorothy E. Grice

This study investigates genetic relationships between OCD, BD, SCZ, and MDD using GWAS data, finding causal effects of OCD on BD, SCZ, and MDD.

BELONG collects DNA and clinical data from 1,250 African ancestry OCD cases to improve genetic research representation and identify OCD risk genes.

This study identifies rare coding variants contributing to OCD risk and shows genetic overlap with CTD and neurodevelopmental disorders, while showing minimal overlap with bipolar disorder and schizophrenia.

This study identifies two novel genetic loci associated with Tourette Syndrome through a genome-wide meta-analysis and integrates functional data to implicate specific genes.

The paper investigates gene-environment interactions related to tic severity by analyzing SNPs from GWASs of Tourette syndrome and related disorders in interaction with pre- and perinatal adversity.

This study develops a Ddx3x haploinsufficient mouse model to investigate DDX3X syndrome, finding developmental and behavioral abnormalities linked to brain structural changes.

The paper identifies two methylation-based episignatures in ADNP syndrome but finds limited correlation with clinical phenotypes.

The paper identifies de novo epigenetic variations in congenital disorders and shows their impact on gene expression and potential diagnostic relevance.