Comparative Multi-omic Mapping of Human Pancreatic Islet Endoplasmic Reticulum and Cytokine Stress Responses Provides Insights into Type 2 Diabetes Genetics
Eishani Kumar Sokolowski, Romy Kursawe, Vijay Selvam, Redwan M. Bhuiyan, Asa Thibodeau, Chi George Zhao, Cassandra Nichole Spracklen, Duygu Ucar, Michael L. Stitzel
This study investigates how human pancreatic islet cells respond to ER and cytokine stress and identifies T2D-associated genetic variants that modulate these responses.
bioRxiv · Feb 17, 2024 · PreprintGenomics