Embryonic lymphocytes contribute to a genetic form of autoimmune inflammation
Sara Cascione, Elena Fontana, Rebecca Scarfò, Rosita Rigoni, Valentina Capo, Elena Draghici, Kerry Dobbs, Luigi Daniele Notarangelo, ANNA MARIA VILLA, Andrea Ditadi
This study shows that embryonic-like progenitors contribute to autoreactive T-cells in Omenn Syndrome, leading to autoimmune inflammation.
bioRxiv · Nov 24, 2023 · PreprintDevelopmental Biology