Systematic review and network meta-analysis of drug combinations suggested by machine learning on genes and proteins, with the aim of improving the effectiveness of Ipilimumab in treating Melanoma.
Danial Safaei, Ali Akbar Kiaei, Mahnaz Boush, Sadegh Abadijou, Alireza Khorramabadi, Nader Salari, Masoud Mohammadi, Elham Parichehreh
This paper proposes a drug combination for Melanoma treatment using machine learning on genes and proteins, showing a 74-fold increase in effectiveness compared to single drugs.
medRxiv · May 13, 2023 · PreprintGenetic & Genomic Medicine