Control of Systemic Iron Homeostasis by the 3' Iron-Responsive Element of Divalent Metal Transporter 1 in Mice.
Elisabeth Tybl, Hiromi Gunshin, Sanjay Gupta, Tomasa Barrientos, Michael Bonadonna, Ferran Celma Nos, Gaël Palais, Zoubida Karim, Mayka Sánchez, Nancy C. Andrews, Bruno Galy
This study shows that the 3' IRE of DMT1 regulates iron homeostasis in mice, promoting intestinal DMT1 expression in early life and suppressing it in adulthood.
HemaSphere · Sep 23, 2020Peer-reviewedMolecular Biology