Identifying Distinct Molecular Response of CAR-T cells to Solid Tumors by Synthetic Single-Cell Transcriptomic Analyses
Yi Hui Luo, Elisabetta Forte, Yoshiaki Tanaka
The paper identifies unique molecular responses of CAR-T cells in solid tumors through single-cell transcriptomic analysis, revealing immunosuppressive subpopulations and PD-1-independent exhaustion-like features.
bioRxiv · Sep 17, 2025 · PreprintCancer Biology